Intimate Setting

20 years experience

Therapeutical Support

Preparation Integration

harmonising Ancient Wisdom and Modern Healing


Embark on a transformative journey with Rejuvyn. Immerse yourself in profound healing through our unique blend of ancient traditions and innovative psilocybin experiences. Discover the empowering unity of mind, body, and spirit.

Contact us for a free consultation

psilocybin mushrooms in a medicine bottle
decorative leaves on a branch

What We Do

Welcome to Rejuvyn

At Rejuvyn we proudly offer a space for those seeking a healing and transformative experience with one of our various psilocybin retreat packages, including a full therapeutic preparation and integration retreat programme designed to deepen your psychedelic experience.

Psilocybin mushrooms and truffles have an ancient history of usage by indigenous cultures around the world for ceremonial and medicinal purposes.  It is believed, based on writings and carvings, that these ceremonies, or ancient psilocybin retreats, were often used for healing and divination. In more recent times psilocybin has become on the cutting edge of psychological health.

It is our mission to combine ancient wisdom with modern technology to expand human consciousness and healing.

Unlock the Power of Psychedelic Healing.

What we work with

What is Psilocybin?

Psilocybin is a psychoactive substance, found in magic mushrooms and truffles which alters your state of consciousness.  Within these altered states you are given an opportunity to gain a deeper understanding of your thought, emotional, and behavioural patterns.

Psilocybin is processed in the body and is transformed into a compound psilocin, which is very similar to serotonin in its chemical structure. Serotonin is a neurotransmitter that is responsible for many functions in the body and brain, including regulating cognition, mood, and perception (Lesch & Waider, 2012).   Due to this similarity, psilocin can interact with a particular serotonin receptor, Serotonin 5-HT2A, highlighted in the scientific literature as being a key mechanism in the reduction of mental health issues, such as depression, anxiety, PTSD, and obsessive compulsive disorder (Zhang & Stackman, 2015).

As more research comes out reporting the transformational nature of this entheogenic medicine, psilocybin is fast becoming the first therapeutical psychedelic in the world (Kargbo, 2020). Found to have an overwhelmingly positive effect on the experience of PTSD, addiction, and depression (Crowe et al., 2023Kisely et al., 2022), Psilocybin inspires connection to the inner-self in a way that allows the individual to gain an alternative perspective on their life situations.

Opening the ‘Critical Period’

Psychedelics, including psilocybin, are quickly becoming known for their positive impact on neuroplasticity and how new neural connections and brain patterns are created and multiplied during psychedelic experience (Vargas et al., 2023).

New research indicates that the creation of new neural pathways does not stop when the effects of the psychedelic wares off. Described as re-opening a ‘critical period’(Nardou et al., 2023), the opportunities provided by psychoactive substances like psilocybin last for a considerable time after the experience itself.  The critical period is a term used to describe when a person is sensitive to learning new patterns and recoding old ones. It is a special time where you can reinforce the tools of personal development and the maintenance of various insights into your daily experience. Within this context the concepts of preparation and integration become more salient and relevant for your experience.

decorative leaves on branches

Awaken Your Potential with Our Guided Psilocybin Retreats.

an old tree bathed in sunlight
decorative leaves on a branch

OUR Approach

Psilocybin Retreats

A Psilocybin retreat in the Netherlands provides a legal space where you can experience the powerful healing effects of this entheogenic medicine within a safe and supportive space. You can choose from several of our psilocybin retreat packages in the Netherlands for your process and we are there to support you making this choice by having a friendly non-binding phone call or by simply answering an email.

With over 20 years of combined experience, our psychedelic facilitators have the expertise to guide you during your psilocybin retreat in a way that is most conducive to creating the optimal environment for your experience and personal goals.

Our therapeutic preparation and integration psilocybin retreat programme is specifically designed to guide you throughout your whole process. Preparation is a big part of integration and allows you to gain clarity of purpose and intention before attending your psilocybin retreat, deepening the healing and insights during your psychedelic experience. Integration is everything and is a standard practice for all our psilocybin retreats. However, within the current programme, the integration phase is a fuller process of expanding and continuing the retreat experience as you are given a deeper opportunity to translate your psychedelic experiences into lasting change.

Finding Healing

How does psilocybin therapy work?

Psilocybin therapy explores the therapeutic potential of psilocybin, the psychoactive compound found in magic truffles and magic mushrooms.

Prior to undergoing psilocybin therapy, individuals undergo a thorough screening process to assess their medical history, mental health conditions, and suitability for the treatment. This is done to ensure the safety and well-being of the participants.

Psilocybin therapy is typically conducted in a controlled and supportive environment, often referred to as the “set and setting.” The setting is designed to create a safe and comfortable space, with consideration given to elements like lighting, music, and supportive therapy professionals. The mindset or “set” of the individual is also important, as they are encouraged to approach the experience with openness, intention, and a willingness to explore their inner experiences.

A trained therapist or facilitator administers a carefully measured dose of psilocybin to the participant. The dosage is determined based on factors such as individual characteristics, therapeutic goals, and the specific research protocol being followed.

During the psilocybin session, individuals are encouraged to lie down, wear an eye mask, and listen to specially curated music. They are supported by trained therapists or facilitators who provide emotional support and guidance throughout the experience. The role of the therapists is to create a safe container, help navigate challenging emotions, and facilitate integration of the insights gained from the experience.

Following the psilocybin session, a crucial aspect of the therapy is the integration process. This involves discussing and reflecting on the experience with the therapist or facilitator, aiming to make meaning out of the insights gained and applying them to one’s daily life. Integration may include individual therapy sessions, group discussions, journaling, or other practices that aid in processing and integrating the transformative aspects of the experience.

Psilocybin therapy often involves follow-up sessions and ongoing support to help individuals integrate their experiences and maintain the therapeutic benefits over time. This may involve additional therapy sessions, personalised support plans, or referrals to other healthcare professionals as needed.

decorative leaves on branches

Discover the Transformative Power of Psilocybin.

Dive Deeper into Knowledge

Frequently Asked Questions

What is the success rate of psilocybin for depression?

The success rate of psilocybin for depression is still an active area of research, and it is important to note that results can vary depending on the specific study design, population, and measures of success used. While more research is needed to determine the precise success rate, early studies have shown promising results.

Several clinical trials have explored the effects of psilocybin-assisted therapy in individuals with treatment-resistant depression, meaning they have not responded adequately to conventional treatments. These studies have reported significant reductions in depressive symptoms and improvements in overall well-being following psilocybin therapy.

For example, a landmark study conducted by Griffiths et al. in 2016 found that a single dose of psilocybin, combined with therapy, led to substantial reductions in depression and anxiety in individuals with life-threatening cancer. Furthermore, the effects persisted for up to six months after the treatment.

Another notable study by Carhart-Harris et al. in 2018 examined the efficacy of psilocybin in treatment-resistant depression. The researchers reported rapid and significant reductions in depressive symptoms, with nearly half of the participants achieving remission at one week following treatment. These effects were sustained at three months post-treatment.

While these studies show promising outcomes, it’s important to interpret the success rate within the context of the specific research population and design. Additionally, long-term follow-up studies are still needed to assess the durability and maintenance of the treatment effects.

Psilocybin therapy for depression is an evolving field, and ongoing research is being conducted to better understand its efficacy, optimal dosing, and long-term outcomes. Consulting with healthcare professionals or organizations involved in psychedelic research can provide more comprehensive and up-to-date information on the success rates of psilocybin therapy for depression.

Does psilocybin increase brain connectivity in people with depression after use?

Recent research suggests that psilocybin may indeed increase brain connectivity in people with depression after use. Several studies have explored the effects of psilocybin on brain activity and connectivity, particularly in individuals with depression.

A notable study conducted by Carhart-Harris et al. in 2017, used functional magnetic resonance imaging (fMRI) to examine the effects of psilocybin on brain connectivity. The researchers found that psilocybin led to increased connectivity between brain regions that were typically disconnected or showed reduced connectivity in individuals with depression. This increased connectivity was associated with long-lasting reductions in depressive symptoms. In a follow-up study these results were verified as it reported long-lasting change.

Another study by Roseman et al. in 2018 investigated the acute and sustained effects of psilocybin on brain connectivity in patients with treatment-resistant depression. The researchers observed increased functional connectivity between key brain regions involved in emotional processing, suggesting that psilocybin may facilitate a more flexible and adaptive brain network.


Get In Touch With Us